Top 10 Best Cities to Visit in South America for Travelers
South America is a continent filled with breathtaking landscapes, rich cultures, and vibrant cities, making it one of the most diverse travel destinations in the world. If you’re wondering which are the best cities to visit in South America, this article will guide you through the top 10 choices. Whether you’re a history buff, nature lover, or simply seeking a new adventure, these cities offer something for everyone. Safety, tourist popularity, and ideal travel times like December are also considered to ensure a memorable and enjoyable trip.

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Why Travel to South America?
South America’s allure comes from its fascinating blend of cultural heritage, natural wonders, and welcoming locals. From the towering peaks of the Andes to the stunning beaches of Brazil and Uruguay, the continent offers a wide range of experiences. Safety is a key consideration for travelers, and this article highlights some of the safest and most tourist-friendly cities in the region.
Best Time to Visit South America
For many cities in South America, December is an excellent time to visit, offering pleasant weather and festive celebrations. Whether you’re looking to enjoy a summer escape in Argentina or partake in colorful cultural events in Colombia, December offers a fantastic opportunity to explore the continent’s best destinations.
Criteria for Choosing the Best Cities to Visit in South America
The cities featured in this list are selected based on a few important factors:
- Safety: These cities are known to be among the safest places to visit in South America.
- Popularity: They are frequently visited by tourists, reflecting their appeal.
- Cultural and Natural Attractions: Each city offers unique experiences, from historical landmarks to natural beauty.
- Best Time to Visit: Cities that are great for visiting in December are prioritized, ensuring favorable weather and festive atmospheres.
Criteria | Description |
Safety | Cities chosen based on low crime rates and tourist-friendly environments. |
Tourist Popularity | The cities attract large numbers of visitors every year. |
Cultural and Natural Attractions | Key sites of interest, including museums, architecture, and natural wonders. |
Best Time to Visit | Highlighting the cities ideal for December vacations due to festivals or climate. |
Top 10 Best Cities to Visit in South America for Travelers
1. Buenos Aires, Argentina
Why Visit: Buenos Aires is a cultural powerhouse, often referred to as the “Paris of South America.” It’s known for its European-inspired architecture, thriving arts scene, and vibrant tango shows. The city is also famous for its mouthwatering cuisine, particularly Argentine steaks.
Must-See Attractions:
- La Boca: A colorful neighborhood with tango performances.
- Plaza de Mayo: Historical square surrounded by important buildings like Casa Rosada.
- Teatro Colón: One of the world’s most prestigious opera houses.
Safety Tips: Buenos Aires is generally safe for tourists, though it’s best to avoid walking alone in less crowded areas at night.
Best Time to Visit: December brings pleasant summer weather, making it perfect for exploring the city’s outdoor attractions.
2. Rio de Janeiro, Brazil
Why Visit: Rio de Janeiro is famous for its stunning beaches, breathtaking views, and iconic landmarks. The vibrant city offers a dynamic mix of urban energy and natural beauty, making it one of the most visited cities in South America.
Must-See Attractions:
- Christ the Redeemer: One of the New Seven Wonders of the World.
- Sugarloaf Mountain: Offers panoramic views of Rio’s coastline.
- Copacabana Beach: A must-visit for beach lovers.
Safety Tips: Stick to tourist areas and avoid traveling late at night in lesser-known neighborhoods.
Best Time to Visit: December is the start of Rio’s summer, perfect for beach activities and sightseeing.
3. Bogotá, Colombia
Why Visit: Bogotá, Colombia’s capital, offers a mix of modern and traditional attractions. With a rich history and thriving arts scene, it’s a city that surprises travelers with its cultural vibrancy and friendliness.
Must-See Attractions:
- Gold Museum: Home to one of the largest collections of pre-Colombian gold artifacts.
- Monserrate: A mountain offering stunning views of the city.
- La Candelaria: The historic center of Bogotá with colorful colonial buildings.
Safety Tips: Bogotá is one of the safest places to visit in South America, but tourists should still take basic precautions like avoiding isolated areas after dark.
Best Time to Visit: December is an excellent time for holiday events and outdoor activities, with mild and comfortable weather.
4. Santiago, Chile
Why Visit: Santiago offers a unique blend of cosmopolitan living and access to the Andes Mountains. Known for its proximity to vineyards and ski resorts, it’s a city where you can experience both urban life and natural beauty.
Must-See Attractions:
- San Cristobal Hill: Provides panoramic views of Santiago.
- Plaza de Armas: The heart of the city’s historic district.
- Bellavista Neighborhood: Famous for its bohemian atmosphere and street art.
Safety Tips: Santiago is a safe city, though pickpocketing can be a concern in busy areas.
Best Time to Visit: December offers warm weather, ideal for exploring the city and surrounding outdoor activities.
5. Lima, Peru
Why Visit: Lima, the capital of Peru, is the gateway to Machu Picchu and boasts an extraordinary culinary scene. The city is rich in colonial history, with plenty of museums and coastal charm.
Must-See Attractions:
- Larco Museum: Houses a vast collection of pre-Colombian art.
- Plaza Mayor: The main square, surrounded by beautiful colonial buildings.
- Barranco: A lively district known for its art galleries and nightlife.
Safety Tips: Stick to well-known tourist areas like Miraflores and Barranco, as these are some of the safest parts of Lima.
Best Time to Visit: December is perfect for enjoying Lima’s coastal attractions, with warm temperatures and clear skies.
6. Cusco, Peru

Why Visit: Cusco, the former capital of the Incan Empire, is a top destination for those seeking to explore ancient history and embark on a journey to Machu Picchu.
Must-See Attractions:
- Sacsayhuamán: An impressive Inca fortress.
- Qorikancha: Once the richest temple in the Inca Empire.
- Plaza de Armas: The vibrant city center surrounded by historical landmarks.
Safety Tips: Cusco is a safe city for tourists, but visitors should be aware of altitude sickness and plan accordingly.
Best Time to Visit: December offers pleasant weather and a festive atmosphere, making it a great time for exploring both the city and nearby Inca ruins.
7. Medellín, Colombi
Why Visit: Known as the “City of Eternal Spring,” Medellín enjoys a mild climate year-round. It’s also famous for its transformation from a turbulent past to a vibrant, innovative city.
Must-See Attractions:
- Comuna 13: A neighborhood known for its street art and community transformation.
- Parque Arví: A beautiful natural park offering eco-tourism activities.
- Antioquia Museum: Home to works by Colombia’s famous artist, Fernando Botero.
Safety Tips: Medellín has greatly improved its safety in recent years, but as with any city, it’s wise to remain cautious in unfamiliar areas.
Best Time to Visit: December is ideal for enjoying Medellín’s outdoor activities and cultural events.
8. Quito, Ecuador
Why Visit: Quito is the capital of Ecuador and is renowned for its well-preserved colonial architecture. The city sits high in the Andes, offering stunning views and unique cultural experiences.
Must-See Attractions:
- Mitad del Mundo: A monument marking the equator line.
- Historic Old Town: A UNESCO World Heritage site.
- El Panecillo: A hill offering panoramic views of the city.
Safety Tips: Quito is generally safe, but it’s important to watch out for petty theft in crowded areas.
Best Time to Visit: December offers cool weather and festive holiday celebrations, perfect for sightseeing.
9. Montevideo, Uruguay
Why Visit: Montevideo, the capital of Uruguay, is known for its relaxed vibe, colonial architecture, and beautiful coastal views. The city is perfect for travelers looking for a more laid-back experience.
Must-See Attractions:
- Solís Theatre: One of the oldest theatres in South America.
- Mercado del Puerto: A bustling marketplace known for its barbecue.
- Ciudad Vieja: The historic old town filled with colonial charm.
Safety Tips: Montevideo is considered one of the safest places to visit in South America, with a low crime rate compared to other capital cities.
Best Time to Visit: December is warm and sunny, ideal for enjoying Montevideo’s beaches and cultural events.
10. Cartagena, Colombia
Why Visit: Cartagena is a coastal city known for its well-preserved colonial architecture and Caribbean beaches. It’s one of the top 10 most visited cities in South America due to its vibrant history and tropical allure.
Must-See Attractions:
- Castillo San Felipe de Barajas: A fortress offering panoramic views of the city.
- Rosario Islands: A perfect spot for a beach getaway.
- Getsemaní: A colorful neighborhood known for its lively street art.
Safety Tips: Cartagena is a safe city for tourists, but it’s always a good idea to stay in well-lit and busy areas at night.
Best Time to Visit: December is ideal for beach lovers and for enjoying the city’s festive atmosphere.
Conclusion
South America is home to some of the world’s most captivating cities, each offering its own blend of culture, history, and natural beauty. Whether you’re planning a December getaway or looking for a new adventure, these best cities to visit in South America provide a safe, enriching, and unforgettable travel experience. From the cosmopolitan energy of Buenos Aires to the colonial charm of Cartagena, these destinations are a must-see for any traveler.

This author’s life has been an adventure. He has visited over 30 countries, and lived in four different states. He is a traveler at heart, but he also loves exploring the outdoors on his bicycle or hiking with his canine companion.